Blastos: Discover What They Are and Where They Come From

In the composition of blood chemistry, the blasts are the abnormal appearance of white blood cells, which are also known by the name of myeloblasts. Specialists only call them blasts, these being very strange and young forms of cells that are responsible for producing blood, but should not.

Unfortunately, blasts do not function as well as normal white blood cells. Performing specific blood tests and finding these white blood cells may indicate the presence of leukemia, but it is worth noting that this disease is only diagnosed by analyzing cells from the bone marrow.

It is for this reason that people with acute myeloid leukemia, or AML for its acronym in English (acute myeloid leukemia), have excess white blood cells in the blood, which is abnormal for its proper functioning.

Signs of acute myeloid leukemia

Acute myeloid leukemia, is also known by the name of blood cancer, which occurs when the bone marrow of the sick person produces myoblasts or blasts, which is an abnormal white blood cell that is too young to produce blood.

The process by which cells are formed, developed and matured in the blood is known as hematopoiesis, this process is responsible for these cells to develop normally in the blood. When people have acute myeloid leukemia, the maturation process of cells is not completed, turning them into abnormal cells that accumulate in the bone marrow.

By accumulating in the bone marrow, the immune system is affected, lowering its defenses and making it prone to possible infections. What specialist doctors recommend in cases where there are recurrent infections is to perform a thorough blood test to rule out these abnormalities.

It is important to highlight that their presence is a sign of leukemia, which places the patient’s life in constant risk.

Appearance of blasts in the blood: Where do they come from?

The appearance of these in the blood is the result of the mutation of all the genetic information of the cells that are developing.

It is for this reason that, given the rapidity with which this type of cells reproduce, for each one that is classified as a myeloblast, it is necessary to have the projection that its production will reach an alarming figure of more than eleven billion cells.

Once cataloged by a blood test, these cells are called leukemic blasts. Unfortunately these types of cells manage to adapt and survive much better in the bloodstream than normal cells.

Types of samples needed to diagnose the presence of blasts in the blood or acute myeloid leukemia

Once the specialist doctor suspects that the patient may have leukemia, he immediately orders a series of tests and samples of blood cells and bone marrow.

Bone marrow samples can be obtained from two very precise tests which are:

Bone marrow biopsy

This type of sample is taken from the back of the pelvic bone, but other bones in the body will also be sampled. If only one sample is needed, it is usually taken from the chest bone.

Bone marrow aspiration

In this type of sample, the specialist doctor makes a small incision where he will insert a needle until he reaches the bone and therefore the bone marrow. Once the marrow is reached, it will extract a liquid portion of it. For bone marrow aspiration, more than one sample may be taken.

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